RENAL DISCOVERIES Extramural Grant Program (EGP), awards grants for innovation, exploration and application of research to advance the knowledge of renal insufficiency and its treatment.
The objective of RENAL DISCOVERIES, EGP is to stimulate and support research in the fields of dialytic therapies chronic kidney disease, and co-morbidities associated with end-stage renal disease (ESRD), with the goal of improving the quality of life and reducing mortality of patients with kidney disease.
An independent international Medical Advisory Board (MAB) – whose membership represents a breadth of scientific knowledge – will evaluate and score each application based on the merit of the submitted proposals as described below. RENAL DISCOVERIES, is a global program that accepts research applications from all regions of the world.
Institution: Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands Title: The peritoneal microvascular endothelial glycocalyx during peritoneal dialysis Sponsor: Raymond Krediet, M.D., Ph.D. Principal Investigator: Raymond Krediet, M.D., Ph.D. Fellow: Carmen Vlahu, M.D.
Institution: St. Joseph's Healthcare, Hamilton/McMaster University, Hamilton, Ontario, Canada Title: Effect of Bio-impedance Analysis vs. Usual Care on Left Ventricular Mass in Peritoneal Dialysis Patients: A Randomized Controlled Trial Sponsor: Alistair Ingram, M.D., FRCP(C) Co-Principal Investigators: Azim Gangji, M.D., MSc., FRCP(C) and Scott Brimble, M.D., MSc., FRCP(C) Fellow: Winnie Su, M.D., FRCP(C)
Institution: The First Affiliated Hospital, Sun Yat-sen University, Guangzhou/Guangdong, China Title: Pathogenesis of Peritoneal Dialysis-related Escherichia Coli Peritonitis Sponsor: Xueqing Yu, M.D., Ph.D. Principal Investigator: Xiao Yang, M.D., Ph.D.
Institution: University Health Network, Toronto, Ontario, Canada Title: Towards a contemporary understanding of diastolic dysfunction in uremia Sponsor: Edward Cole, M.D., FRCP(C) Principal Investigator: Christopher Chan, M.D., FRCP(C)
Overview of the 2010 Grant Program
The aim of the 2010 RENAL DISCOVERIES, EGP is to support Patient-Oriented Research in academic nephrology training centers around the world. Grants will be awarded for Patient-Oriented Research in the area of Home Dialysis and/or co-morbidities in patients treated with Home Dialysis.
Deadline for Letter of Intent: April 15, 2010
Deadline for Full Grant Application: September 15, 2010
For this award, patient-oriented research is defined as research conducted with human subjects (or on material of human origin such as tissues, specimens and cognitive phenomena) for whom an investigator interacts with human subjects. Patient-oriented research includes mechanisms of human disease; General Clinical Research Center based pathophysiologic studies, therapeutic interventions, clinical trials, behavioral studies, epidemiology (including database research), outcomes and health service research, and development of new technologies. Excluded from this definition are in vitro studies that utilize human tissues that cannot be linked to a living individual.
Grant Elements
Grants may include either an Operating Grant or a combined Operating Grant and Fellowship Training Grant, as defined below:
Operating Grant: The Operating Grant will support patient-oriented research overseen by the faculty of the sponsoring institution. The research must be focused on one of the following areas:
Dialytic therapies in the home
Co-morbidities in patients receiving home ESRD therapy
Transplant focused research will not be considered for funding
Fellowship Training Grant: The Fellowship Training Grant will support a minimum of one (1) research fellow at the institution during the course of the grant period. A Fellow is defined as a physician with nephrology training, or one who is committed to nephrology training, who will be trained in research and/or home dialysis clinical practice. The Fellow(s) need not be identified at the time of submitting the Letter of Intent (LOI) but must be identified at the time of the final grant submission.
In order to be considered for an award, an application need not include both the operating and fellowship training grant components described above. For those applying for an operating grant only, please note that preference will be given to institutions with demonstrated fellowship training programs and those that describe training opportunities for fellows within their application.
Funding: A maximum of USD$125,000 per year for three years (including institutional overhead not to exceed 20%) will be awarded to each 2010 grant winner.
Up to four grants will be awarded and funded in 2010
A minimum of one grant will be awarded to low, and middle-income countries as defined by the World Bank List of Economies, July 2009 (http://go.worldbank.org/D7SN0B8YU0)
Application Process
Forms and writing instrucitons will be available November 16, 2009.
Four grants are selected, by an independent Medical Advisory Board, and awarded yearly.
If you would like more information regarding this research grant program, or would like to be added to our mailing list, please click here to send an e-mail to our program administrator.
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